The HiSeq1500 system provides power and efficiency for large-scale genomics. Innovative engineering
combines with proven SBS technology to set new standards in output, simplicity, and cost-effectiveness.
Two high output options offer greatest depth of coverage, and a rapid run provides quick results.
u Dual-surface imaging—The HiSeq 1500 uses a 4-camera epifluorescence system with cutting-edge
scanning technology to enable dual surface imaging.
u On-instrument cluster generation—The HiSeq 1500 provides the option of Rapid Run mode, which
includes on-instrument cluster generation.
u High-capacity reagent chiller—The reagent compartment is a high-capacity chiller that holds enough
reagents for the entire sequencing run.
u Integrated fluidics for paired-end runs—Integrated paired-end fluidics provide reagents from the reagent
compartment to the flow cell for Read 2 resynthesis and for indexed sequencing.
u Interface control options—The instrument software interface provides options for setting up a run and
operating the instrument. Use the touch screen monitor or the integrated keyboard to provide input.
u Real-time base calling—The instrument software extracts intensities from images and performs qualityscored base calling on the instrument computer. This method allows monitoring of quality metrics during
the run and saves time during subsequent data analysis.
Downstream analysis of sequencing data can be performed with Illumina analysis software or third-party
software on IlluminaCompute, Illumina BaseSpace, or a custom infrastructure.